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Scientia Pharmaceutica

Volume 79 (2011) | Issue 3

Review

Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances
Sarvesh K. Paliwal, Ankita Narayan Verma, Shailendra Paliwal
389–428
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Original Papers and Short Communications

Pharmaceutical & Analytical Chemistry

Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-tumor Agents
Samir M. El-Moghazy, Diaa A. Ibrahim, Nagwa M. Abdelgawad, Nahla A. H. Farag, Ahmad S. El-Khouly
429–447
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Design, Synthesis and Biological Evaluation of New 5,5-Diarylhydantoin Derivatives as Selective Cyclooxygenase-2 Inhibitors
Afshin Zarghi, Farin Sattary Javid, Razieh Ghodsi, Orkideh G. Dadrass, Bahram Daraei, Mehdi Hedayati
449–460
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Molecular Modeling on Structure-Function Analysis of Human Progesterone Receptor Modulators
Ria Pal, Md Ataul Islam, Tabassum Hossain, Achintya Saha
461–477
DetailsFull Text (pdf) | Supporting Information (pdf, < 0.3 MB)

Preformulation Studies of Zidovudine Derivatives: Acid Dissociation Constants, Differential Scanning Calorimetry, Thermogravimetry, X-Ray Powder Diffractometry and Aqueous Stability Studies
Mónica A. Raviolo, Margarita C. Briñón
479–491
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Feed Forward Artificial Neural Network: Tool for Early Detection of Ovarian Cancer
Ankita Thakur, Vijay Mishra, Sunil K. Jain
493–505
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Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents
Ekhlass Nassar, Hatem A. Abdel-Aziz, Hany S. Ibrahim, Ahmed M. Mansour
507–524
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A Rapid, Stability Indicating RP-UPLC Method for Simultaneous Determination of Ambroxol Hydrochloride, Cetirizine Hydrochloride and Antimicrobial Preservatives in Liquid Pharmaceutical Formulation
Rakshit Kanubhai Trivedi, Mukesh C. Patel, Sushant B. Jadhav
525–543
DetailsFull Text (pdf)

Validated RP-HPLC Method for Simultaneous Quantitation of Losartan Potassium and Metolazone in Bulk Drug and Formulation
Ramkumar Dubey, Vidhya K. Bhusari, Sunil R. Dhaneshwar
545–554
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Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurities in Verapamil Hydrochloride
Viswanathan Srinivasan, Hariharan Sivaramakrishnan, Balakrishnan Karthikeyan
555–568
DetailsFull Text (pdf)

Validation of a Flow Cytometry Based Binding Assay for Evaluation of Monoclonal Antibody Recognizing EGF Receptor
Mercedes Cedeño-Arias, Javier Sánchez-Ramírez, Rancés Blanco-Santana, Enrique Rengifo-Calzado
569–581
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Development and Validation of Amisulpride in Human Plasma by HPLC Coupled with Tandem Mass Spectrometry and its Application to a Pharmacokinetic Study
Ramakotaiah Mogili, Kanchanamala Kanala, Balasekhara Reddy Challa, Babu Rao Chandu, Chandrasekhar Kottapalli Bannoth
583–599
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Synthesis, Characterization and Quantification of Simvastatin Metabolites and Impurities
Manish S. Bhatia, Swapnil D. Jadhav, Neela M. Bhatia, Prafulla B. Choudhari, Kundan B. Ingale
601–614
DetailsFull Text (pdf)

Pharmacology & Clinical Pharmacy

In Vitro and In Vivo Effects of Natural Putative Secretagogues of Glucagon-Like Peptide-1 (GLP-1)
Eamon P. Rafferty, Alastair R. Wylie, Chris T. Elliott, Olivier P. Chevallier, David J. Grieve, Brian D. Green
615–621
DetailsFull Text (pdf)

Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines
Mohamed E. E. Shams, Mohammed M. H. Al-Gayyar, Enaase A. M. E. Barakat
623–634
DetailsFull Text (pdf)

Pharmaceutical Technology & Biopharmaceutics

Enhanced Antihypertensive Activity of Candesartan Cilexetil Nanosuspension: Formulation, Characterization and Pharmacodynamic Study
Chetan Detroja, Sandip Chavhan, Krutika Sawant
635–651
DetailsFull Text (pdf)

Taste Masked Microspheres of Ofloxacin: Formulation and Evaluation of Orodispersible Tablets
Karan Malik, Gurpreet Arora, Inderbir Singh
653–672
DetailsFull Text (pdf)

Amoxicillin Loaded Chitosan–Alginate Polyelectrolyte Complex Nanoparticles as Mucopenetrating Delivery System for H. Pylori
Saahil Arora, Sankalp Gupta, Raj K. Narang, Ramji D. Budhiraja
673–694
DetailsFull Text (pdf)


Editorial

The Successful Relaunch of Scientia Pharmaceutica Continues Achieving Success
Wolfgang Kubelka, Gernot A. Eller
695–699
DetailsFull Text (pdf)

Book Reviews

"Characterization of Nanoparticles Intended for Drug Delivery"
701
Full Text (pdf)

"Teedrogen und Phytopharmaka"
703
Full Text (pdf)








 
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