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Scientia Pharmaceutica

Volume 83 (2015) | Issue 2

Original Papers

Pharmaceutical & Analytical Chemistry

Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing Quinone Moiety
Khrystyna Bolibrukh, Svyatoslav Polovkovych, Omar Khoumeri, Tetyana Halenova, Irina Nikolaeva, Olexiy Savchuk, Thierry Terme, Patrice Vanelle, Vira Lubenets, Volodymyr Novikov
221–231
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An Alternative Approach to Isoganciclovir: A Prominent Impurity in the Antiviral Drug Ganciclovir
Dhanraj T. S. S. Sundaram, Anand G. Kamat, Koilpillai Joseph Prabahar, Peruri Badarinadh Gupta, Battula Venkateswara Rao, Sanasi Paul Douglas
233–241
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Molecular Docking Studies of Phytocompounds From Phyllanthus Species as Potential Chronic Pain Modulators
Atul R. Chopade, Fahim J. Sayyad, Yogesh V. Pore
243–267
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A Validated HPLC/MS Limit Test Method for a Potential Genotoxic Impurity in Cilostazol and its Quantification in the API and in the Commercially Available Drug Product
Luigi Bray, Luca Monzani, Enrico Brunoldi, Pietro Allegrini
269–278
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Development of a Stability-Indicating Stereoselective Method for the Quantification of Enantiomer in Drug Ssubstance and Pharmaceutical Dosage form of Rosuvastatin Calcium by Enhanced Approach
Gangireddy Rajendra Reddy, Papammagari Ravindra Reddy, Polisetty Siva Jyothi
279–296
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Forced Degradation Behaviour of Fluphenazine Hydrochloride by LC and Characterization of its Oxidative Degradation Product by LC–MS/MS
Kashyap N. Thummar, Dilip J. Ghava, Anvi Mistry, Ashish Vachhani, Navin R. Sheth
297–309
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Development of a Forced Degradation Profile of Alosetron by Single Mode Reversed-Phase HPLC, LC-MS, and its Validation
Yamjala Karthik, Basuvan Babu, Subramania Nainar Meyyanathan
311–320
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Validated Stability-Indicating RP-HPLC Method for Estimation of Degradation Behaviour of Organic Peroxide and Third Generation Synthetic Retinoids in Topical Pharmaceutical Dosage Formulation
Chinmoy Roy, Lalatendu Panigrahi, Jitamanyu Chakrabarty
321–338
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Pharmacology & Clinical Pharmacy

Rapid, Cost-Effective Pre-Clinical Method to Screen for Pro- or Antiarrhythmic Effects of Substances in an Isolated Heart Preparation
John Joseph Borg
339–352
DetailsFull Text (pdf) | Supporting Information (pdf, < 0.1 MB) 

Pharmacognosy & Phytomedicine

Screening of Panamanian Plant Extracts for Pesticidal Properties, and HPLC-Based Identification of Active Compounds
Niels Guldbrandsen, Maria De Mieri, Mahabir Gupta, Tobias Seiser, Christine Wiebe, Joachim Dickhaut, Rüdiger Reingruber, Oliver Sorgenfrei, Matthias Hamburger
353–367
DetailsFull Text (pdf) | Supporting Information (pdf, ca. 0.5 MB) 

An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona bark
Steen Honoré Hansen, Else Holmfred, Claus Cornett, Carla Maldonado, Nina Rønsted
369–376
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FT-IR Method for the Quantification of Isoflavonol Glycosides in Nutritional Supplements of Soy (Glycine max (L.) Merr.)
Katharina Mulsow, Juliane Eidenschink, Matthias F. Melzig
377–386
DetailsFull Text (pdf)

Pharmaceutical Technology & Biopharmaceutics

Influence of Ethanol as Co-Solvent in Cyclodextrin Inclusion Complexation: A Molecular Dynamics Study
Kanokthip Boonyarattanakalin, Helmut Viernstein, Peter Wolschann, Luckhana Lawtrakul
387–399
DetailsFull Text (pdf)

Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients
Monika Mueller, Maybelle Q. T. Loh, Pete Gagnon
401–410
DetailsFull Text (pdf)






 
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