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Scientia Pharmacuetica

Volume 81 (2013) | Issue 3

Original Papers and Short Communications

Pharmaceutical & Analytical Chemistry

Preparation and First Preclinical Evaluation of [18F]FE@SNAP: A Potential PET Tracer for the Melanin Concentrating Hormone Receptor 1 (MCHR1)
Cécile Philippe, Lukas Nics, Markus Zeilinger, Eva Schirmer, Helmut Spreitzer, Georgios Karanikas, Rupert Lanzenberger, Helmut Viernstein, Wolfgang Wadsak, Markus Mitterhauser
625–639
DetailsFull Text (pdf)

Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics
Jürgen Krauss, Carina Gratzl, Verena Sturm, Christoph Müller, Verena Staudacher, Christoph Q. Schmidt, Franz Bracher
641–650
DetailsFull Text (pdf)

Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
Srinivas Garaga, Ambati V. Raghava Reddy, Koilpillai Joseph Prabahar, Raghu Babu Korupolu, Paul Douglas Sanasi
651–662
DetailsFull Text (pdf) | Supporting Information (pdf, ca. 1.0 MB) 

Synthesis of 1,2,3-Triazole Derivatives and Evaluation of their Anticancer Activity
Nazariy Pokhodylo, Olga Shyyka, Vasyl Matiychuk
663–676
DetailsFull Text (pdf)

How to Solve the Problems of Docking into a Symmetric Binding Site: The Example of the hERG Channel
Andrea Schiesaro, Lars Richter, Gerhard F. Ecker
677–682
DetailsFull Text (pdf)

Identification and Characterization of Process Related Impurities of Trans-Resveratrol
Balasubramanian Sivakumar, Raman Murugan, Annamalai Baskaran, Bhausaheb Pandharinath Khadangale, Saravanan Murugan, Udayampalayam Palanisamy Senthilkumar
683–695
DetailsFull Text (pdf)

Development and Validation of a Stability-Indicating RP-HPLC Method for Determination of Process Related Impurities and Degradation Droducts of Rabeprazole Sodium in Pharmaceutical Formulation
Navneet Kumar, Dhanaraj Sangeetha
697–711
DetailsFull Text (pdf)

Validated Stability-Indicating HPLC-DAD Method for the Simultaneous Determination of Diclofenac Sodium and Diflunisal in Their Combined Dosage Form
Rasha A. Shaalan , Tarek S. Belal
713–731
DetailsFull Text (pdf)

Validation of a Stability-Indicating Hydrophilic Interaction Liquid Chromatographic Method for the Quantitative Determination of Vitamin K3 (Menadione Sodium Bisulfite) in Injectable Solution Formulation
Mashhour M. Ghanem, Saleh A. Abu-Lafi, Hussein O. Hallak
733–747
DetailsFull Text (pdf)

Pharmacology & Clinical Pharmacy

Pharmacological Analysis of the Rat Femoral Artery Response to Bradykinin
Miroslav Radenković, Marko Stojanović, Nebojša Skorupan and Milica Prostran
749–761
DetailsFull Text (pdf)

Nitric Oxide is a Potential Diagnostic Marker for Hepatocellular Carcinoma
Laila A. Eissa, Nada H. Eisa, Mohamed A. Ebrahim, Maha Ragab, Amal M. El-Gayar
763–775
DetailsFull Text (pdf)

A Randomized, Crossover, Single-Dose Bioequivalence Study of Two Extended Release Tablets of Donepezil 23 mg in Healthy Human Volunteers under Fasting and Fed State
Chaitanya Gadiko, Sudhakar Koundinya Tippabhotla, Satyanarayana Thota, Ramakrishna Battula, Sohel Md. Khan, Venkateswarlu Vobalaboina
777–791
DetailsFull Text (pdf)

Pharmacognosy & Phytomedicine

Compounds from Gum Ammoniacum with Acetylcholinesterase Inhibitory Activity
Hamid-Reza Adhami, Johannes Lutz, Hanspeter Kählig, Martin Zehl, Liselotte Krenn
793–805
DetailsFull Text (pdf)

Quantification of Sesquiterpene Lactones in Asteraceae Plant Extracts: Evaluation of the Allergenic Potential
Helena Salapovic, Johannes Geier, Gottfried Reznicek
807–818
DetailsFull Text (pdf)

Cytotoxic Compounds from Brucea mollis
Mai Hung Thanh Tung, Ho Viet Đuc, Tran Thu Huong, Nguyen Thanh Duong, Do Thi Phuong, Do Thi Thao, Bui Huu Tai, Young Ho Kim, Tran The Bach, Nguyen Manh Cuong
819–831
DetailsFull Text (pdf)

A Poly-Ingredient Formulation Bresol® Ameliorates Experimental Chronic Obstructive Pulmonary Disease (COPD) in Rats
Mohamed Rafiq, Gollapalle Lakshminarayanashastry Viswanatha, Dattatray Anturlikar Suryakanth, Mohammed Azeemuddin, Mahalingaiah Jagadeesh, Krishna Dhanush, Pralhad Sadashiv Patki
833–842
DetailsFull Text (pdf)

Pharmaceutical Technology & Biopharmaceutics

Intranasal Delivery of Chitosan Nanoparticles for Migraine Therapy
Neha Gulati, Upendra Nagaich, Shubhini A. Saraf
843–854
DetailsFull Text (pdf)  | Full Text incl. Erratum (pdf)

Evidence of Polymorphism on the Antitrypanosomal Naphthoquinone (4E)-2-(1H-Pyrazol-3-ylamino)-4-(1H-pyrazol-3-ylimino)naphthalen-1(4H)-one
Norma R. Sperandeo, Sonia N. Faudone
855–864
DetailsFull Text (pdf)

Rivastigmine Loaded L-Lactide-Depsipeptide Polymeric Nanoparticles: Decisive Formulation Variables Optimization
Kunal Pagar, Pradeep Vavia
865–885
DetailsFull Text (pdf)






 
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