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Scientia Pharmaceutica

Volume 80 (2012) | Issue 2

Original Papers

Pharmaceutical & Analytical Chemistry

A QSAR Study of Matrix Metalloproteinases Type 2 (MMP-2) Inhibitors with Cinnamoyl Pyrrolidine Derivatives
Eduardo Borges de Melo
265–281
DetailsFull Text (pdf) | Supporting Information (pdf, < 0.1 MB)

Pharmacophore Identification and QSAR Studies on Substituted Benzoxazinone as Antiplatelet Agents: kNN-MFA Approach
Prafulla B. Choudhari, Manish S. Bhatia, Swapnil D. Jadhav
283–294
DetailsFull Text (pdf)

Identification and Characterization of an Oxidative Degradation Product of Fexofenadine, Development and Validation of a Stability Indicating RP-UPLC Method for the Estimation of Process Related Impurities and Degradation Products of Fexofenadine in Pharmaceutical Formulations
Bhupendrasinh Vaghela, Surendra Singh Rao, Annarapu Malleshwar Reddy, Panuganti Venkatesh, Navneet Kumar
295–309
DetailsFull Text (pdf)

Rapid Determination of Diclofenac in Pharmaceutical Formulations by Capillary Zone Electrophoresis
Bodo Lachmann, Martin Kratzel, Christian R. Noe
311–316
DetailsFull Text (pdf)

Stability-Indicating HPLC Method for Posaconazole Bulk Assay
Cássia V. Garcia, Gislaine R. Costa, Andreas S. L. Mendez
317–327
DetailsFull Text (pdf)

Identification, Isolation and Characterization of an Unknown Impurity of Varenicline
Balasubramanian Satheesh, Kondayampettai K. Sree Ganesh, Dhandayutham Saravanan
329–336
DetailsFull Text (pdf)

Application of HPLC for the Simultaneous Determination of Aceclofenac, Paracetamol and Tramadol Hydrochloride in Pharmaceutical Dosage Form
Preeti Chandra, Atul Singh Rathore, Sathiyanarayanan Lohidasan, Kakasaheb Ramoo Mahadik
337–351
DetailsFull Text (pdf)

Development of a Stability Indicating RP-UPLC Method for Rapid Determination of Metaxalone and its Degradation Products in Solid Oral Dosage Form
Rakshit Kanubhai Trivedi, Mukesh C. Patel
353–366
DetailsFull Text (pdf)

Method Development and Validation of Almotriptan in Human Plasma by HPLC Tandem Mass Spectrometry: Application to Pharmacokinetic Study
Konda Ravikumar, Babu Rao Chandu, Balasekhara Reddy Challa, Kottapalli B. Chandrasekhar
367–378
DetailsFull Text (pdf)

Stability-Indicating LC Method for the Determination of Prasugrel Hydrochloride in Pharmaceutical Dosage Form
Vinod K. Ahirrao, Chabutai S. Patil, Saroj B. Bembalkar, Sanjay B. Ubale, Rajendra P. Marathe, Rajesh B. Nawale, Mahadev G. Landge, Rajendra P. Pawar
379–391
DetailsFull Text (pdf)

Development and Validation of a Stability-Indicating RP-UPLC Method for Determination of Rosuvastatin and Related Substances in Pharmaceutical Dosage Form
Harshal Kanubhai Trivedi, Mukesh C. Patel
393–406
DetailsFull Text (pdf)

Stability-Indicating Liquid Chromatographic Method for the Quantification of the New Antipsychotic Agent Asenapine in Bulk and in Pharmaceutical Formulation
Usmangani K. Chhalotiya, Kashyap K. Bhatt, Dimal A. Shah, Jigar R. Patel
407–417
DetailsFull Text (pdf)

Pharmacology & Clinical Pharmacy

Randomized, Crossover and Single-Dose Bioequivalence Study of Two Oral Desogestrel Formulations (Film-Coated Tablets of 75 µg) in Healthy Female Volunteers
María Ángeles Pena, Emilio Sanz, Silvia Francisco, Ainhara Alonso, Zurine Abajo, Izaskun Felipe, Jaume Pascual, Digna Tost, Sandra Bailac
419–431
DetailsFull Text (pdf)

Pharmacognosy & Phytomedicine

Characterization of Constituents and Anthelmintic Properties of Hagenia abyssinica
Henrieke Thomsen, Katrin Reider, Katrin Franke, Ludger A. Wessjohann, Jennifer Keiser, Ermias Dagne, Norbert Arnold
433–446
DetailsFull Text (pdf) 

Protective Properties of Laggera alata Extract and its Principle Components Against D-Galactosamine-Injured Hepatocytes
Yi-Hang Wu, Bing-Jie Hao, E Shen, Qing-Li Meng, Ming-Hui Hu, Yu Zhao
447–456
DetailsFull Text (pdf) 

Relaxant Effect of Essential Oil of Artemisia herba-alba Asso. on Rodent Jejunum Contractions
Mohammed Aziz, Ahmed Karim, El Mokhtar El Ouariachi, Abdelhamid Bouyanzer, Souliman Amrani, Hassane Mekhfi, Abderrahim Ziyyat, Ahmed Melhaoui, Mohamed Bnouham, Abdelkhaleq Legssyer
457–467
DetailsFull Text (pdf) 

A New Isoflavone Glycoside from Dalbergia vacciniifolia (Fabaceae)
Ester Innocent
469–474
DetailsFull Text (pdf) 

In Vitro Drug Absorption Enhancement Effects of Aloe vera and Aloe ferox
Catharina Beneke, Alvaro Viljoen, Josias Hamman
475–486
DetailsFull Text (pdf)

Pharmaceutical Technology & Biopharmaceutics

Equilibrium and Release Properties of Aqueous Dispersions of Non Steroidal Antiinflammatory Drugs Complexed with Polyelectrolyte Eudragit E 100
Daniela Alejandra Quinteros, Daniel Alberto Allemandi, Ruben Hilario Manzo
487–496
DetailsFull Text (pdf)






 
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